MDS, epididymis luminal protein 2, mitochondrial import stimulation factor (MSF) L subunit, Mitochondrial import stimulation factor L subunit, MSF L, protein kinase C inhibitor protein-1
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western blot analysis of 293T, PC-3 and A431 lysates using YWHAE Recombinant Rabbit Monoclonal Antibody (YWHAE/8636R).
Western blot analysis of Human Brain, Mouse Brain, Rat Brain, Hamster Brain, Guinea pig Brain, Human Lungs, Mouse Lungs, Rat Lungs, Hamster Lungs and Guinea pig Lungs tissue lysates using YWHAE Recombinant Rabbit Monoclonal Antibody (YWHAE/8636R).
