Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric juice. They show extensive diversity in distribution and in their subcellular localization. CA III (carbonic anhydrase III), also known as Car3 or CA3, is a 260 amino acid cytoplasmic protein that is specifically expressed in muscle. Belonging to the a-carbonic anhydrase family, CA III is activated by proton donors such as imidazole and dipeptide histidylhistidine, and is inhibited by coumarins and sulfonamide derivatives such as acetazolamide.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified CA3 Mouse Monoclonal Antibody (CA3/7883). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human skeletal muscle stained with CA3 Mouse Monoclonal Antibody (CA3/7883). Inset: PBS instead of primary antibody, secondary only negative control.
Western blot analysis of RH-30 cell lysate using CA3 Mouse Monoclonal Antibody (CA3/7883).
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