Recombinant Carbonic Anhydrase VIII Antibody, IgG1, Clone: [rCA8/8835], Mouse, Monoclonal

Artikelnummer: NBT-767-MSM7-P1
Artikelname: Recombinant Carbonic Anhydrase VIII Antibody, IgG1, Clone: [rCA8/8835], Mouse, Monoclonal
Artikelnummer: NBT-767-MSM7-P1
Hersteller Artikelnummer: 767-MSM7-P1
Alternativnummer: NBT-767-MSM7-P1-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant full-length human CA8 protein
Alternative Synonym: CA-VIII, CALS, CARP, MGC120502, MGC99509
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in CA8 gene causes neuropathology, such as ataxia, mild mental retardation and the predisposition to quadrupedal gait. It is also associated with the development of colorectal and lung cancers. Additionally, it is upregulated in various cancers.
Klonalität: Monoclonal
Klon-Bezeichnung: [rCA8/8835]
Molekulargewicht: 32.97kDa
Isotyp: IgG1
NCBI: 767
UniProt: P35219
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western Blot Analysis of K-562 cell lysate using CA8 Mouse Recombinant Monoclonal Antibody (rCA8/8835 ).
Western Blot Analysis of K-562 cell lysate using CA8 Mouse Recombinant Monoclonal Antibody (rCA8/8835 ).
Western Blot Analysis of MCF7 cell lysate using CA8 Mouse Recombinant Monoclonal Antibody (rCA8/8835 ).
SDS-PAGE Analysis of Purified CA8 Recombinant Mouse Monoclonal Antibody (rCA8/8835). Confirmation of Purity and Integrity of Antibody.