Recombinant Prostein (p501S) / Solute Carrier Family 45 Member 3 (SLC45A3) Antibody, Clone: [SLC45A3/7176R], Rabbit, Monoclonal

Produktübersicht

• Artikelname: Recombinant Prostein (p501S) / Solute Carrier Family 45 Member 3 (SLC45A3) Antibody, Clone: [SLC45A3/7176R], Rabbit, Monoclonal
• Artikelnummer: NBT-85414-RBM6-P1ABX
• Hersteller Artikelnummer: 85414-RBM6-P1ABX
• Alternativnummer: NBT-85414-RBM6-P1ABX-100
• Hersteller: NeoBiotechnologies
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Synthesized peptides to the N terminus of human SLC45A3 (prostein) protein
• Alternative Synonym: IPCA 2, IPCA 8, IPCA6, Prostate cancer associated gene / protein 2 (PCANAP2), Prostate cancer associated gene / protein 6 (PCANAP6), Prostate cancer associated gene / protein 8 (PCANAP8),

Produktbeschreibung

Human prostein is a 553 aa protein identified by cDNA library subtraction and subsequent high throughput microarray screening of prostate cancer. Prostein has multiple transmembrane domains. Prostein has been shown to be uniquely expressed in normal and cancerous prostatic tissues. By immunohistochemistry, prostein is expressed in the vast majority of normal and malignant prostatic tissues, regardless of grade and metastatic status. No protein expression is detected in normal and malignant tissue samples representing the great majority of essential tissues and tumors. In particular, prostein is expressed in most of poorly differentiated prostatic carcinoma, including small cell prostate carcinoma. Prostein is more specific and sensitive for prostatic carcinomas than PSA and PSAP.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [SLC45A3/7176R]
• Molekulargewicht: 59kDa
• NCBI: 85414
• UniProt: Q96JT2
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Recombinant Monoclonal Antibody

Anwendungsbeschreibung

• Anwendungsbeschreibung: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT for 20 minutes),Optimal diluti

Bilder

SDS-PAGE Analysis of Purified Prostein Recombi

Formalin-fixed, paraffin-embedded human prostate stained with Prostein (p501S) Recombinant Rabbit Monoclonal Antibody (SLC45A3/7176R). Inset: PBS instead of primary antibody, secondary only negative control.

SDS-PAGE Analysis of Purified Prostein Recombinant Rabbit Monoclonal Antibody (SLC45A3/7176R). Confirmation of Purity and Integrity of Antibody.

Analysis of Protein Array containing more than 19,000 full-length human proteins using Prostein (p501S) Recombinant Rabbit Monoclonal Antibody (SLC45A3/7176R). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.