Recombinant fragment (around aa200-400) of human IL18RAP protein (exact sequence is proprietary)
Alternative Synonym:
IL18RAP, Accessory protein like, AcPL, CD218 antigen-like family member B, CDw218b, IL 18RAcP, IL 1R accessory protein like, IL 1R7, IL 1RAcPL, IL18R Beta, IL18RAP, IL18Rbeta, Interleukin 18 receptor accessory protein, Interleukin-1 receptor 7, Interleukin-18 receptor beta chain
The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohns disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
