Recombinant protein corresponding to the N-terminal fragment of cyclin A protein
Alternative Synonym:
CCN1, CCNA, CCNA2, CCNA2_HUMAN, Cyclin A2
It recognizes a protein of 54kDa, which is identified as cyclin A. Its epitope is located amino acids 144-148 of human Cyclin A2. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while cyclin B is a critical regulator of mitosis. Mutation or disruption of normal cyclin A expression causes cells to arrest in G2-phase.
200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western Blot Analysis of EL4 lysate using Cyclin A2 Recombinant Mouse Monoclonal Antibody (r6-i6).
SDS-PAGE Analysis of Purified CCNA2 Recombinant Mouse Monoclonal Antibody (r6E6). Confirmation of Purity and Integrity of Antibody.
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