BCL10 (MALT-Lymphoma Marker) Antibody, IgG1, Clone: [151], Mouse, Monoclonal

Artikelnummer: NBT-8915-MSM2-P1ABX
Artikelname: BCL10 (MALT-Lymphoma Marker) Antibody, IgG1, Clone: [151], Mouse, Monoclonal
Artikelnummer: NBT-8915-MSM2-P1ABX
Hersteller Artikelnummer: 8915-MSM2-P1ABX
Alternativnummer: NBT-8915-MSM2-P1ABX-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human
Immunogen: Human BCL10 recombinant protein (epitope aa122-168)
Alternative Synonym: B-cell CLL/lymphoma 10, B-cell leukemia/lymphoma 10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, caspase-recruiting domain-containing protein, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, Cellular-E10 (cE10), CIPER, hCLAP, mE10, R-RCD1
BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1,14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Klonalität: Monoclonal
Klon-Bezeichnung: [151]
Molekulargewicht: 33kDa
Isotyp: IgG1
NCBI: 8915
UniProt: O95999
Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Monoclonal Antibody
Anwendungsbeschreibung: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes), Optimal dilution
Formalin-fixed, paraffin-embedded human Tonsil stained with BCL-10 Monoclonal Antibody (151).
Formalin-fixed, paraffin-embedded human Tonsil stained with BCL-10 Monoclonal Antibody (151).