Cyclin E (G1/S-Phase Cyclin) Antibody, Clone: [CCNE1/2587], Mouse, Monoclonal

Produktübersicht

• Artikelname: Cyclin E (G1/S-Phase Cyclin) Antibody, Clone: [CCNE1/2587], Mouse, Monoclonal
• Artikelnummer: NBT-898-MSM2-P1
• Hersteller Artikelnummer: 898-MSM2-P1
• Alternativnummer: NBT-898-MSM2-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: ELISA
• Spezies Reaktivität: Human
• Immunogen: Recombinant human Cyclin E (CCNE1) protein fragment (around aa 10-176) (exact sequence is proprietary)
• Alternative Synonym: CCNE1, Cyclin E1, G1/S-specific cyclin-E1

Produktbeschreibung

Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [CCNE1/2587]
• Molekulargewicht: 53kDa.
• NCBI: 898
• UniProt: P24864
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

SDS-PAGE Analysis of Purified Cyclin E Mouse Monoclonal Antibody (CCNE1/2587). Confirmation of Integrity and Purity of Antibody.