Recombinant Cyclin E (G1/S-Phase Cyclin) Antibody, IgG2a, Clone: [r13A3], Mouse, Monoclonal

Produktübersicht

• Artikelname: Recombinant Cyclin E (G1/S-Phase Cyclin) Antibody, IgG2a, Clone: [r13A3], Mouse, Monoclonal
• Artikelnummer: NBT-898-MSM9-P1
• Hersteller Artikelnummer: 898-MSM9-P1
• Alternativnummer: NBT-898-MSM9-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human
• Immunogen: Prokaryotic recombinant fusion protein corresponding to the full length cyclin E molecule
• Alternative Synonym: CCNE1, Cyclin E1, G1/S-specific cyclin-E1

Produktbeschreibung

Cyclin E was identified as a protein which would complement cyclin mutations in yeast and mammalian cells. Overexpression of cyclin E shortens the length of the G1 phase, accelerating progression of the cell cycle into S phase. The activity of cyclin E is mediated through its activation of cyclin dependent kinase 2 (cdk2) protein and is modulated by the presence of tumor suppressor proteins such as p16.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [r13A3]
• Molekulargewicht: 53kDa
• Isotyp: IgG2a
• NCBI: 898
• UniProt: P24864
• Formulierung: 200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

SDS-PAGE Analysis of Purified Cyclin E Recombinant Mouse Monoclonal Antibody (r13A3). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human placenta stained with Cyclin E Recombinant Rabbit Mouse Antibody (r13A3). Inset: PBS instead of primary antibody, secondary only negative control.