CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Anwendungsbeschreibung:
Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 mi
Formalin-fixed, paraffin-embedded human Tonsil (10X) stained with CD6 Monoclonal Antibody (3F7B5).
Formalin-fixed, paraffin-embedded human Tonsil (20X) stained with CD6 Monoclonal Antibody (3F7B5).
Flow Cytometric Analysis of MOLT-4 cells. CD6 Monoclonal
Formalin-fixed, paraffin-embedded human Tonsil (10X) stained with CD6 Monoclonal Antibody (3F7B5).
Formalin-fixed, paraffin-embedded human Tonsil (20X) stained with CD6 Monoclonal Antibody (3F7B5).
Flow Cytometric Analysis of MOLT-4 cells. CD6 Monoclonal Antibody (3F7B5) followed by goat anti-Mouse IgG-CF488 (Blue), Isotype control (Red).
Immunofluorescence staining of MOLT-4 cells using CD6 MAb (3F7B5) followed by goat anti-Mouse IgG conjugated to CF488 (green). Nuclei are stained with Reddot.
SDS-PAGE Analysis of Purified CD6 Monoclonal Antibody (3F7B5). Confirmation of Purity and Integrity of Antibody.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
