Recombinant CD14 (Monocyte / Macrophage Marker) Antibody, Clone: [LPSR/4180R], Rabbit, Monoclonal

Produktübersicht

• Artikelname: Recombinant CD14 (Monocyte / Macrophage Marker) Antibody, Clone: [LPSR/4180R], Rabbit, Monoclonal
• Artikelnummer: NBT-929-RBM14-P1
• Hersteller Artikelnummer: 929-RBM14-P1
• Alternativnummer: NBT-929-RBM14-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide corresponding to residues withinaa1-100 of CD14 was used as an immunogen.
• Alternative Synonym: Lipopolysaccharide receptor, LPSR, Mo2, Monocyte Differentiation Antigen 14, Myeloid cell-specific leucine-rich glycoprotein

Produktbeschreibung

CD14 is receptor for endotoxin and apoptotic cells. It is expressed by monocytes/histiocytes, Langerhans cells, follicular dendritic reticulum cells, neutrophils (weakly), and endothelial cells of the liver sinusoids.CD14 is detected in myeloid leukemias with monoblastic/monocytic differentiation, and in histiocytic neoplasms like histiocytic lymphoma, Langerhans cell histiocytosis and giant cell tumor. In cultures, a subpopulation of Kaposi sarcoma cells express CD14. In differential diagnosis, CD14 is more specific than CD68 in the identification of monocytes/histiocytes and associated neoplasias.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [LPSR/4180R]
• Molekulargewicht: 40kDa
• NCBI: 929
• UniProt: P08571
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Formalin-fixed, paraffin-embedded human tonsil stained with CD14 Rabbit Recombinant Monoclonal Antibody (LPSR/4180R).

Formalin-fixed, paraffin-embedded human tonsil stained with CD14 Rabbit Recombinant Monoclonal Antibody (LPSR/4180R).