Prokaryotic recombinant protein corresponding to 124 amino acids of the external N-terminus of the CD83 molecule.
Alternative Synonym:
BL11, HB15, B-cell activation protein
CD83 antigen, a member of the immunoglobulin superfamily, is a useful marker of mature and activated dendritic cells. These include Langerhans cells in the skin, peripheral blood dendritic cells and interdigitating reticulum cells within the T cell zones of lymphoid organs. Human early pregnancy decidua contains immunostimulatory CD83 antigen positive dendritic cells. Some germinal centre B cells and activated peripheral lymphocytes also express CD83 antigen. CD83 is also used as a marker for Hodgkin,Aos lymphoma, Reed Sternberg cells and breast carcinoma.
200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified CD83 Recombinant Mouse Monoclonal Antibody (r1H4b). Confirmation of Purity and Integrity of Antibody.
Western Blot Analysis of RH-30 and PC-3 cell lysates using CD83 Recombinant Mouse Monoclonal Antibody (r1H4b).
Formalin-fixed, paraffin-embedded human tonsil stained with CD83 Recombinant Mouse Monoclonal Antibody (r1H4b). Inset: PBS instead of primary antibody, secondary only negative control.
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