Adiponectin (Marker of Obesity) Antibody, IgG1, Clone: [ADPN/4256], Mouse, Monoclonal
Artikelnummer:
NBT-9370-MSM6-P1ABX
Hersteller Artikelnummer:
9370-MSM6-P1ABX
Alternativnummer:
NBT-9370-MSM6-P1ABX-100
Hersteller:
NeoBiotechnologies
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
ELISA, IHC
Spezies Reaktivität:
Human
Immunogen:
Synthetic peptide corresponding to the tail region of the Adiponectin molecule.
Alternative Synonym:
Adiponectin, Adipocyte complement-related 30kDa protein (ACRP30), Adipocyte-specific secretory protein, Adiponectin, C1Q and collagen domain containing (ACDC), ADIPOQ, Adipose most abundant gene transcript 1 protein, Adipose specific collagen like factor, ADIPQTL1, ADPN, APM-1, Gelatin-binding protein 28 (GBP28)
This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore, adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism. Clone ADPN/4256 is used to detect plasma adiponectin concentrations. Clone ADPN/4256 is also used in a combination ELISA with clone ADPN/4255, acting as the capture antibody.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Anwendungsbeschreibung:
ELISA (For coating, use antibody without BSA), ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed
SDS-PAGE Analysis of Purified Ad
Formalin-fixed, paraffin-embedded human kidney stained with Adiponectin Mouse Monoclonal Antibody (ADPN/4256).
Formalin-fixed, paraffin-embedded human kidney stained with Adiponectin Mouse Monoclonal Antibody (ADPN/4256).
SDS-PAGE Analysis of Purified Adiponectin Mouse Monoclonal Antibody (ADPN/4256) Confirmation of Integrity and Purity of Antibody.
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