CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Antibody, IgG2b, Clone: [MSVA-027M], Mouse, Monoclonal

Produktübersicht

• Artikelname: CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Antibody, IgG2b, Clone: [MSVA-027M], Mouse, Monoclonal
• Artikelnummer: NBT-939-MSM26-P0
• Hersteller Artikelnummer: 939-MSM26-P0
• Alternativnummer: NBT-939-MSM26-P0-20
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant human CD27 protein fragment (aa 28-170) (exact sequence is proprietary)
• Alternative Synonym: LPFS2, S152, T cell activation antigen S152, T-cell activation antigen CD27, T14, TNFRSF7, TNFSF7, Tp55, Tumor necrosis factor receptor superfamily member 7

Produktbeschreibung

Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NF B and SAPK/JNK and induces apoptosis.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [MSVA-027M]
• Molekulargewicht: 120kDa
• Isotyp: IgG2b
• NCBI: 939
• UniProt: P26842
• Formulierung: Ab purified from Bioreactor Concentrate by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide.

Bilder

CD27 antigen Mouse Monoclonal Antibody (MSVA-027M) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.