Recombinant CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Antibody, Clone: [LPFS2/2034R], Rabbit, Monoclonal

Produktübersicht

• Artikelname: Recombinant CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Antibody, Clone: [LPFS2/2034R], Rabbit, Monoclonal
• Artikelnummer: NBT-939-RBM4-P1
• Hersteller Artikelnummer: 939-RBM4-P1
• Alternativnummer: NBT-939-RBM4-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant human full-length CD22 protein (exact sequence is proprietary)
• Alternative Synonym: LPFS2, S152, T cell activation antigen S152, T-cell activation antigen CD27, T14, TNFRSF7, TNFSF7, Tp55, Tumor necrosis factor receptor superfamily member 7

Produktbeschreibung

Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [LPFS2/2034R]
• Molekulargewicht: 120kDa
• NCBI: 939
• UniProt: P26842
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Formalin-fixed, paraffin-embedded human Lymph Node stained with CD27 Rabbit Recombinant Monoclonal Antibody (LPFS2/2034R).

SDS-PAGE Analysis of Purified CD27 Rabbit Recombinant Monoclonal Antibody (LPFS2/2034R). Confirmation of Integrity and Purity of Antibody.