CD44v4 (Marker of Tumor Metastasis) Antibody, IgG2a, Clone: [CD44v4/1219], Mouse, Monoclonal

Artikelnummer: NBT-960-MSM6-P1
Artikelname: CD44v4 (Marker of Tumor Metastasis) Antibody, IgG2a, Clone: [CD44v4/1219], Mouse, Monoclonal
Artikelnummer: NBT-960-MSM6-P1
Hersteller Artikelnummer: 960-MSM6-P1
Alternativnummer: NBT-960-MSM6-P1-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human
Immunogen: Recombinant fragment corresponding to the v4 domain of human CD44
Alternative Synonym: LHR, BA-1, chondroitin sulfate proteoglycan 8 (CSPG8), Epican, Extracellular Matrix Receptor III (ECM III), GP90 Lymphocyte Homing Adhesion Receptor, HCAM, HCELL, hematopoietic cell E- and L-selectin ligand, Heparan Sulfate Proteoglycan, Hermes Antigen, HAS, HUTCH I, Hyaluronate Receptor, Indian blood group, Inlu Related p80 Glycoprotein, Ly 24, MDU2, MDU3, MIC4, MUTCH I, Phagocytic Glycoprotein 1 (PGP-1)
This antibody recognizes an epitope encoded by exon v4 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA.The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.
Klonalität: Monoclonal
Klon-Bezeichnung: [CD44v4/1219]
Molekulargewicht: 80-95kDa
Isotyp: IgG2a
NCBI: 960
UniProt: P16070
Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human Cervical Squamous Cell Carcinoma stained with CD44v4 Mouse Monoclonal Antibody (CD44v4/1219)
Formalin-fixed, paraffin-embedded human Tongue Squamous Cell Carcinoma stained with CD44v4 Mouse Monoclonal Antibody (CD44v4/1219)
SDS-PAGE Analysis of Purified CD44v4 Mouse Monoclonal Antibody (CD44v4/1219). Confirmation of Purity and Integrity of Antibody.