CD47 / IAP (Integrin Associated Protein) Antibody, IgG1, Clone: [B6H12.2], Mouse, Monoclonal

Produktübersicht

• Artikelname: CD47 / IAP (Integrin Associated Protein) Antibody, IgG1, Clone: [B6H12.2], Mouse, Monoclonal
• Artikelnummer: NBT-961-MSM1-P1
• Hersteller Artikelnummer: 961-MSM1-P1
• Alternativnummer: NBT-961-MSM1-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FC, Functional Studies, IF, WB
• Spezies Reaktivität: Human
• Immunogen: Intact CD47 Purified from placenta
• Alternative Synonym: Antigenic Surface Determinant Protein OA3, IAP, Integrin Associated Protein, Integrin Associated Signal Transducer, MER6, OA3, Protein MER6, Rh Related Antigen

Produktbeschreibung

This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [B6H12.2]
• Molekulargewicht: ~50kDa
• Isotyp: IgG1
• NCBI: 961
• UniProt: Q08722
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Flow Cytometric Analysis of live Jurkat cells. CD47 Mouse Monoclonal Antibod

Immunofluorescent staining of PFA-fixed MCF-7 cells. CD47 Mouse Monoclonal Antibody (B6H12.2) followed by goat anti-Mouse IgG-CF488 (green). Nuclei are stained with Redot (red).

Flow Cytometric Analysis of live Jurkat cells. CD47 Mouse Monoclonal Antibody (B6H12.2) followed by goat anti-mouse IgG-CF488 (Blue), Isotype Control (Red).

SDS-PAGE Analysis Purified CD47 Mouse Monoclonal Antibody (B6H12.2). Confirmation of Purity and Integrity of Antibody.

Immunofluorescent image of live Jurkat cells. CD47 Mouse Monoclonal Antibody (B6H12.2) followed by goat anti-mouse IgG-CF488 (green).

Immunofluorescent image of PFA-fixed Jurkat cells.CD47 Mouse Monoclonal Antibody (B6H12.2) followed bygoat anti-mouse IgG-CF488 (green).

Flow Cytometric Analysis of PFA-fixed Jurkat cells.CD47 Mouse Monoclonal Antibody (B6H12.2) followed bygoat anti-mouse IgG-CF488 (Blue), Isotype Control (Red).