Plasma Cell Marker Antibody, IgG2a, Clone: [LIV3G11, same as 7B18], Mouse, Monoclonal
Artikelnummer:
NBT-MSM1-47-P0
Hersteller Artikelnummer:
MSM1-47-P0
Alternativnummer:
NBT-MSM1-47-P0-20,NBT-MSM1-47-P0-100
Hersteller:
NeoBiotechnologies
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC
Spezies Reaktivität:
Human
Immunogen:
Pancreatic cancer-related mucin
Alternative Synonym:
Plasma B cell, Plasmocytes
It recognizes an intra-cytoplasmic antigen, which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm, their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This MAb superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this MAb is not suitable for staining frozen tissues.
Klonalität:
Monoclonal
Klon-Bezeichnung:
[LIV3G11, same as 7B18]
Molekulargewicht:
Not Known
Isotyp:
IgG2a
NCBI:
Not Known
Formulierung:
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Anwendungsbeschreibung:
Immunohistochemistry (Formalin-fixed) (0.1-0.2ug/ml for 30 minutes at RT) [(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes), Optimal dilu
Formalin-fixed, paraffin-embedded human Tonsil stained with Plasma Cell Marker Monoclonal Antibody (LIV3G11).
SDS-PAGE Analysis of Purified Plasma-Cells Mouse Monoclonal Antibody(LIV3G11). Confirmation of Purity and Integrity of Antibody.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
