Lewis A (Blood Group Antigen) Antibody, IgG1, Clone: [SPM279], Mouse, Monoclonal

Produktübersicht

• Artikelname: Lewis A (Blood Group Antigen) Antibody, IgG1, Clone: [SPM279], Mouse, Monoclonal
• Artikelnummer: NBT-MSM1X-311-P1
• Hersteller Artikelnummer: MSM1X-311-P1
• Alternativnummer: NBT-MSM1X-311-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FC, IF, IHC
• Spezies Reaktivität: Human, Mouse
• Immunogen: Mucins isolated from ovarian cyst fluid
• Alternative Synonym: Lewis A antigen

Produktbeschreibung

Recognizes a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [SPM279]
• Molekulargewicht: Multiple
• Isotyp: IgG1
• NCBI: Not Applicable
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with Lewis A Monoclonal Antibody (SPM279).