A portion of amino acids 41-76 (BH3 domain) from the human protein was used as the immunogen for this Bax antibody.
Bax belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bax forms a heterodimer with BCL2, and functions as an apoptot