MET Antibody (HGFR), Clone: [4AT44], Mouse, Monoclonal
Artikelnummer:
NSJ-F40179-0.08ML
Hersteller Artikelnummer:
F40179-0.08ML
Alternativnummer:
NSJ-F40179-0.08ML
Hersteller:
NSJ Bioreagents
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
ELISA, IF, IHC, WB
Spezies Reaktivität:
Human, Mouse
Immunogen:
This MET antibody was produced from mice immunized with purified recombinant protein encoding the catalytic domain of human MET/HGFR.
The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.