SUMO1 Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: SUMO1 Antibody, Rabbit, Polyclonal
• Artikelnummer: NSJ-F42010-0.4ML
• Hersteller Artikelnummer: F42010-0.4ML
• Alternativnummer: NSJ-F42010-0.4ML
• Hersteller: NSJ Bioreagents
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, FACS, IF, IHC, WB
• Spezies Reaktivität: Human
• Immunogen: This SUMO1 antibody was produced from rabbits immunized with human SUMO1 recombinant protein.

Produktbeschreibung

Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. The SUMO family consists of SUMO1 and closely related homologs SUMO2, SUMO3, and SUMO4. Sumoylation has been shown to regulate a wide range of proteins, including MDM2, PIAS, PML, RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c-Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, PARK2, WRN, Sp100, IkB-alpha, Androgen receptor (AR), GLUT1/4, CaMK, DNMT3B, TDG, HIF1A, CHD3, EXOSC9, RAD51, and viral targets such as CMV-IE1/2, EBV-BZLF1, and HPV/BPV-E1.

Produkteigenschaften

• Klonalität: Polyclonal
• UniProt: P63165
• Reinheit: Antigen affinity
• Formulierung: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
• Anwendungsbeschreibung: Titration of the SUMO1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.