A human recombinant protein of amino acids 1-297 was used as the immunogen for the CDK1 antibody.
Cyclin Dependent Kinase 1 plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset, promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis.