A portion of amino acids 195-225 from the human protein was used as the immunogen for the TMED4 antibody.
Transmembrane emp24 domain-containing protein 4 is involved in vesicular protein trafficking, mainly in the early secretory pathway. targeting. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis (By similarity).
