A portion of amino acids 196-230 from the human protein was used as the immunogen for the GLI1 antibody.
Glioma associated oncogene 1 acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
