SCAP Antibody / SREBP cleavage-activating protein, Rabbit, Polyclonal

Produktübersicht

• Artikelname: SCAP Antibody / SREBP cleavage-activating protein, Rabbit, Polyclonal
• Artikelnummer: NSJ-F54258-0.08ML
• Hersteller Artikelnummer: F54258-0.08ML
• Alternativnummer: NSJ-F54258-0.08ML
• Hersteller: NSJ Bioreagents
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FACS, IF, IHC-P, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: A portion of amino acids 604-632 from the human protein were used as the immunogen for the SCAP antibody.

Produktbeschreibung

SCAP is a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.

Produkteigenschaften

• Klonalität: Polyclonal
• UniProt: Q12770
• Reinheit: Antigen affinity purified
• Formulierung: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: Western blot: 1:1000-1:2000,Immunohistochemistry (FFPE): 1:50-1:100,Flow cytometry: 1:25 (1x10e6 cells),Immunofluorescence: 1:50-1:100
• Anwendungsbeschreibung: The stated application concentrations are suggested starting points. Titration of the SCAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.