Glutaminase Antibody / GLS, Rabbit, Polyclonal

Artikelnummer: NSJ-F54260-0.05ML
Artikelname: Glutaminase Antibody / GLS, Rabbit, Polyclonal
Artikelnummer: NSJ-F54260-0.05ML
Hersteller Artikelnummer: F54260-0.05ML
Alternativnummer: NSJ-F54260-0.05ML
Hersteller: NSJ Bioreagents
Wirt: Rabbit
Kategorie: Antikörper
Applikation: FACS, IF, IHC-P, WB
Spezies Reaktivität: Human, Mouse, Rat
Immunogen: A portion of amino acids 516-545 from the human protein were used as the immunogen for the Glutaminase antibody.
Sahai (1983) demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter (Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.
Klonalität: Polyclonal
UniProt: O94925
Reinheit: Antigen affinity purified
Formulierung: In 1X PBS, pH 7.4, with 0.09% sodium azide
Antibody Type: Primary Antibody
Application Verdünnung: Western blot: 1:1000-1:2000,Immunofluorescence: 1:25,Immunohistochemistry (FFPE): 1:100-1:200,Flow cytometry: 1:25 (per 1x10e6 cells)
Anwendungsbeschreibung: The stated application concentrations are suggested starting points. Titration of the Glutaminase antibody may be required due to differences in protocols and secondary/substrate sensitivity.