A portion of amino acids 100-128 from the human protein was used as the immunogen for the HBA2 antibody.
HBA2 is a key component of hemoglobin, the protein responsible for transporting oxygen from the lungs to the rest of the body. Together with HBA1, this protein forms a tetramer that binds to oxygen molecules and carries them through the bloodstream. While HBA1 is typically more abundant in adults, HBA2 is essential during fetal development and plays a vital role in ensuring the proper oxygenation of tissues in the growing fetus. Research has shown that mutations in the HBA2 gene can lead to various blood disorders, such as alpha-thalassemia, a condition characterized by reduced production of alpha-globin chains.
