MICB Antibody / MHC class I polypeptide-related sequence B, Rabbit, Polyclonal
Artikelnummer:
NSJ-R32254
Hersteller Artikelnummer:
R32254
Alternativnummer:
NSJ-R32254
Hersteller:
NSJ Bioreagents
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
FACS, WB
Spezies Reaktivität:
Human, Mouse
Immunogen:
Amino acids AEPHSLRYNLMVLSQDESVQSGFLAE of human MICB were used as the immunogen for the MICB antibody.
MHC class I polypeptide-related sequence B is a protein that in humans is encoded by the MICB gene. This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alpha-beta T cells, and gamma-delta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.
