SSH3BP1 Antibody / ABI1, Rabbit, Polyclonal

Produktübersicht

• Artikelname: SSH3BP1 Antibody / ABI1, Rabbit, Polyclonal
• Artikelnummer: NSJ-R32280
• Hersteller Artikelnummer: R32280
• Alternativnummer: NSJ-R32280
• Hersteller: NSJ Bioreagents
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FACS, IF, IHC-P, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Amino acids HGVKWLKAKHGNNQPARTGTLSRTN of human SSH3BP1 were used as the immunogen for the SSH3BP1 antibody.

Produktbeschreibung

SSH3BP1 is also known as ABI1. ABI1 is a human homolog of mouse Abl-interactor-1 (Abi1), mapped on 10p11.2. ABI1 participates in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor (GEF) activities. It dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA, but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins. ABI1 plays a role in the leukemogenesis by translocating to MLL.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Isotyp: Rabbit IgG
• UniProt: Q8IZP0
• Puffer: Lyophilized from 1X PBS with 2% Trehalose
• Reinheit: Antigen affinity
• Formulierung: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Target-Kategorie: SSH3BP1
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: Western blot: 0.1-0.5ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Flow cytometry: 1-3ug/10 6 cells,Immunofluorescence: 5ug/ml
• Anwendungsbeschreibung: Optimal dilution of the SSH3BP1 antibody should be determined by the researcher.

Bilder

IHC testing of FFPE mouse brain with SSH3BP1 antibody. HIER: Boil the paraffin sections