An E.coli-derived zebrafish Rrm1 recombinant protein (amino acids A129-Q730) was used as the immunogen for the Zebrafish Rrm1 antibody.
Predicted to enable ATP binding activity and ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Predicted to be involved in deoxyribonucleotide biosynthetic process. Predicted to be located in cytoplasm. Predicted to be part of ribonucleoside-diphosphate reductase complex. Is expressed in several structures, including immature eye, nervous system, neural tube, presumptive telencephalon, and tail bud. Human ortholog(s) of this gene implicated in chronic progressive external ophthalmoplegia. Orthologous to human RRM1 (ribonucleotide reductase catalytic subunit M1).
