EGF Receptor Antibody, Clone: [B1D8], Mouse, Monoclonal

Produktübersicht

• Artikelname: EGF Receptor Antibody, Clone: [B1D8], Mouse, Monoclonal
• Artikelnummer: NSJ-V2106-100UG
• Hersteller Artikelnummer: V2106-100UG
• Alternativnummer: NSJ-V2106-100UG
• Hersteller: NSJ Bioreagents
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: Blocking, FACS, IP, NeA, Purification
• Spezies Reaktivität: Human
• Immunogen: Microsomes from A431 cells were used as the immunogen for this antibody.

Produktbeschreibung

This antibody reacts with the extracellular domain of EGF receptor and blocks the EGF/TGFa-induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGF receptor.EGFR is type I receptor tyrosine kinase with sequence homology to ErbB2, -3 -4 or HER2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGFa), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Klon-Bezeichnung: [B1D8]
• Isotyp: Mouse IgG2a, kappa
• NCBI: 1956
• Puffer: 1X PBS, pH 7.4
• Reinheit: Protein G purified monoclonal antibody
• Formulierung: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Target-Kategorie: EGF Receptor / EGFR
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: Affinity purification (order BSA/sodium azide-free format for coupling),Blocks ligand-induced activation of EGFR,Inhibits proliferation of A431 cells (order BSA/azide-free format),Arrests tumor growth in vivo (order BSA/azide-free format),Immunoprecipitat
• Anwendungsbeschreibung: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.