PAX5 Antibody, Clone: [PCRP-PAX5-1B1], Mouse, Monoclonal

Artikelnummer: NSJ-V3906-20UG
Artikelname: PAX5 Antibody, Clone: [PCRP-PAX5-1B1], Mouse, Monoclonal
Artikelnummer: NSJ-V3906-20UG
Hersteller Artikelnummer: V3906-20UG
Alternativnummer: NSJ-V3906-20UG
Hersteller: NSJ Bioreagents
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC-P, WB
Immunogen: Full length human recombinant protein was used as the immunogen for this PAX5 antibody.
The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.
Klonalität: Monoclonal
Klon-Bezeichnung: [PCRP-PAX5-1B1]
UniProt: Q02548
Reinheit: Protein G affinity chromatography
Formulierung: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Antibody Type: Primary Antibody
Application Verdünnung: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Western bot: 2-4ug/ml
Anwendungsbeschreibung: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the PAX5 antibody to be titered up or down for optimal performance.