Purified recombinant human IFN-gamma was used as the immunogen for the Interferon gamma antibody.
Recognizes a protein of 20-25kDa, identified as human interferon. This mAb is specific to human IFN-gamma and recognizes both recombinant and native human IFN-gamma. T lymphocytes and NK cells mainly produce IFN-gamma. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN-A/B (type I interferon).
