CD47 Antibody / IAP, Clone: [CD47/2937], Mouse, Monoclonal

Artikelnummer: NSJ-V7536-20UG
Artikelname: CD47 Antibody / IAP, Clone: [CD47/2937], Mouse, Monoclonal
Artikelnummer: NSJ-V7536-20UG
Hersteller Artikelnummer: V7536-20UG
Alternativnummer: NSJ-V7536-20UG
Hersteller: NSJ Bioreagents
Wirt: Mouse
Kategorie: Antikörper
Applikation: ELISA, IHC-P, WB
Spezies Reaktivität: Human
Immunogen: Amino acids 18-135 from the human protein were used as the immunogen for the CD47 antibody.
This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
Klonalität: Monoclonal
Klon-Bezeichnung: [CD47/2937]
UniProt: Q08722
Reinheit: Protein G affinity chromatography
Formulierung: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Antibody Type: Primary Antibody
Application Verdünnung: ELISA: order BSA/sodium azide-free format for coating,Western blot: 1-2ug/ml for 60 min at RT,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Anwendungsbeschreibung: Optimal dilution of the CD47 antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.