CD43 Antibody, Clone: [CDLA43-2], Mouse, Monoclonal

Artikelnummer: NSJ-V7572-20UG
Artikelname: CD43 Antibody, Clone: [CDLA43-2], Mouse, Monoclonal
Artikelnummer: NSJ-V7572-20UG
Hersteller Artikelnummer: V7572-20UG
Alternativnummer: NSJ-V7572-20UG
Hersteller: NSJ Bioreagents
Wirt: Mouse
Kategorie: Antikörper
Applikation: FACS, IF, IHC-P, WB
Spezies Reaktivität: Human
Immunogen: Recombinant full-length human SPN protein was used as the immunogen for the CD43 antibody.
CD43 is one of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity). [UniProt]
Klonalität: Monoclonal
Klon-Bezeichnung: [CDLA43-2]
UniProt: P16150
Reinheit: Protein G affinity chromatography
Formulierung: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Antibody Type: Primary Antibody
Application Verdünnung: Western blot: 1-2ug/ml,Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT,Prediluted IHC only format: incubate for 30 min at RT (1)
Anwendungsbeschreibung: Optimal dilution of the CD43 antibody should be determined by the researcher.