CD43 Antibody, Clone: [CDLA43-2], Mouse, Monoclonal

Artikelnummer: NSJ-V7572IHC-7ML
Artikelname: CD43 Antibody, Clone: [CDLA43-2], Mouse, Monoclonal
Artikelnummer: NSJ-V7572IHC-7ML
Hersteller Artikelnummer: V7572IHC-7ML
Alternativnummer: NSJ-V7572IHC-7ML
Hersteller: NSJ Bioreagents
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC-P
Spezies Reaktivität: Human
Immunogen: Recombinant full-length human SPN protein was used as the immunogen for the CD43 antibody.
CD43 is one of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity). [UniProt]
Klonalität: Monoclonal
Klon-Bezeichnung: [CDLA43-2]
UniProt: P16150
Reinheit: Protein G affinity chromatography
Formulierung: Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*
Antibody Type: Primary Antibody
Application Verdünnung: The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Anwendungsbeschreibung: Optimal dilution of the CD43 antibody should be determined by the researcher.