Amino acids 28-162 were used as the immunogen for the recombinant Erythropoietin antibody.
Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. [UniProt]
The stated application concentrations are suggested starting points. Titration of the Erythropoietin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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