INSM2 Antibody / Insulinoma Associated 2, Clone: [INSM2/4291], Mouse, Monoclonal

Artikelnummer: NSJ-V8752-100UG
Artikelname: INSM2 Antibody / Insulinoma Associated 2, Clone: [INSM2/4291], Mouse, Monoclonal
Artikelnummer: NSJ-V8752-100UG
Hersteller Artikelnummer: V8752-100UG
Alternativnummer: NSJ-V8752-100UG
Hersteller: NSJ Bioreagents
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC-P
Spezies Reaktivität: Human
Immunogen: A portion of amino acids 432-540 from the human protein was used as the immunogen for the INSM2 antibody.
IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription. INSM2 may function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.
Klonalität: Monoclonal
Klon-Bezeichnung: [INSM2/4291]
UniProt: Q96T92
Reinheit: Protein G affinity chromatography
Formulierung: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Antibody Type: Primary Antibody
Application Verdünnung: Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
Anwendungsbeschreibung: Optimal dilution of the INSM2 antibody should be determined by the researcher.