Anti-Progesterone Receptor Antibody, Clone: [SPM566], Mouse, Monoclonal

Artikelnummer: NSJ-V9066IHC-7ML
Artikelname: Anti-Progesterone Receptor Antibody, Clone: [SPM566], Mouse, Monoclonal
Artikelnummer: NSJ-V9066IHC-7ML
Hersteller Artikelnummer: V9066IHC-7ML
Alternativnummer: NSJ-V9066IHC-7ML
Hersteller: NSJ Bioreagents
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC-P
Spezies Reaktivität: Human
Immunogen: Recombinant human protein was used as the immunogen for this anti-Progesterone Receptor antibody.
This mAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone.
Klonalität: Monoclonal
Klon-Bezeichnung: [SPM566]
UniProt: P06401
Reinheit: Protein G affinity chromatography
Formulierung: Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*
Antibody Type: Primary Antibody
Application Verdünnung: The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Anwendungsbeschreibung: The optimal dilution of the anti-Progesterone Receptor antibody for each application should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.