IRF3 Antibody / Interferon regulatory factor 3, Clone: [PCRP-IRF3-6C8], Mouse, Monoclonal

Produktübersicht

• Artikelname: IRF3 Antibody / Interferon regulatory factor 3, Clone: [PCRP-IRF3-6C8], Mouse, Monoclonal
• Artikelnummer: NSJ-V9201-100UG
• Hersteller Artikelnummer: V9201-100UG
• Alternativnummer: NSJ-V9201-100UG
• Hersteller: NSJ Bioreagents
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FACS, IF, WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant full-length human IRF3 protein was used as the immunogen for the IRF3 antibody.

Produktbeschreibung

In the absence of viral infection, IRF3 is maintained as a monomer in an autoinhibited state. Phosphorylation by TBK1 and IKBKE disrupts this autoinhibition leading to the liberation of the DNA-binding and dimerization activities and its nuclear localization where it can activate type I IFN and ISG genes. [UniProt]

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [PCRP-IRF3-6C8]
• UniProt: Q14653
• Reinheit: Protein A/G affinity
• Formulierung: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Western blot: 1-2ug/ml
• Anwendungsbeschreibung: Optimal dilution of the IRF3 antibody should be determined by the researcher.