recombinant human TGFB1 Plus

Produktübersicht

• Artikelname: recombinant human TGFB1 Plus
• Artikelnummer: QKN-QK010-TGFB1-5000
• Hersteller Artikelnummer: QK010-TGFB1-5000
• Alternativnummer: QKN-QK010-TGFB1-5000
• Hersteller: Qkine
• Kategorie: Biochemikalien
• Applikation: Stem cell, organoid
• Spezies Reaktivität: Human

Zusatzinformationen

Qk010 Recombinant human TGF-β1 PLUS protein is the first truly animal-free recombinant human transforming growth factor beta 1 (TGF-β1) protein for chemically-defined stem cell media. Our recombinant human TGF-β1 PLUS protein has been extensively validated, including for its ability to maintain iPSC pluripotency by the specialist stem cell biotechnology company, Stemnovate, Cambridge, UK.

 

Recombinant human transforming growth factor-beta 1 (TGF-β1) protein is an essential growth factor in many iPSC and ESC maintenance media, including the  commonly used chemically-defined E8 based stem cell culture medias. To date, recombinant human TGF-β1 has only been produced from mammalian cell protein expression systems (HEK or CHO), where endogenous protein contaminants, cost and animal-free status is a challenge.  Our protein experts have optimized TGF-β1 allowing us to produce the first highly bioactive protein in an E. coli fully animal-free expression system. 

As part of our ongoing mission to re-define industry standards for growth factor and cytokine biochemical quality, we’re delighted to introduce the first optimized, truly animal-free recombinant human TGF-β1 for our stem cell maintenance range.

Benefits:

• Truly animal-free alternative for chemically-defined stem cell culture media
• High potency in iPSC culture with high pluripotency (Nanog) marker expression
• High purity, extensive biochemical data and exceptional batch-to-batch consistency

Summary: Qk010 is a modified version of human TGF-β1 protein (Uniprot: P01137), which has been optimized for high purity expression in E. coli. The mature protein is a disulfide-linked dimer.

Molecular mass: ~24 kDa (for the dimer)

Form: Protein is provided lyophilized from a fully volatile solution. Animal-derived component and carrier protein-free.

Produkteigenschaften

• Molekulargewicht: ~24 kDa (for the dimer)
• UniProt: P01137
• Expression System: E.coli
• CAS Nummer: 3-4 working days

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