WM3758 is a metastatic human melanoma cell line. This cell line contains a Q61L mutation at position 61 in the N-RAS gene. The Q61L mutation results in an amino acid substitution at position 61 in NRAS, from a glutamine (Q) to a leucine (L). This cell line expresses wild type BRAF, c-KIT, and CDK4 genes. WM3758 cells match with WM3682 and WM3702. These cells produce xenograft tumors when injected into immunocompromised mice.
Konzentration:
1.0 million cells/mL (Count By Hemocytometer)
Puffer:
None
Quelle:
Human
Formulierung:
Frozen Cell Suspension
Anwendungsbeschreibung:
The key applications of these cell lines include genetic studies, xenograft production, drug testing, and drug target discovery. These cell line models can be used in various biological assays, and for identifying critical target genes, and cell signaling pathways.
Human melanoma tumor cells with known gene mutations, disease stage, STR, and RPPA profiling
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