WM853-2 Non-Viable Cell Pellet

Produktübersicht

• Artikelname: WM853-2 Non-Viable Cell Pellet
• Artikelnummer: ROC-WM853-2-03-0005
• Hersteller Artikelnummer: WM853-2-03-0005
• Alternativnummer: ROC-WM853-2-03-0005
• Hersteller: Rockland Immunochemicals
• Kategorie: Zellen/Zellkultur
• Konjugation: Unconjugated
• Alternative Synonym: Melanoma, patient derived tumor, tumor models, skin cancer, xenograft

Produktbeschreibung

Non-viable cell pellet was generated from cell line WM853-2. WM853-2 is a tumorigenic (VGP) primary melanoma cell line with competence for metastasis. This cell line was established from site on the back in a 71-year-old male. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line expresses wild type PTEN, N-RAS, c-KIT, and CDK4 genes. WM853-2 cells produce xenograft tumors when injected into immunocompromised mice.

Produkteigenschaften

• Konzentration: 5.0 million cells (Count By Hemocytometer)
• Puffer: None
• Quelle: Human
• Formulierung: Frozen Cell Pellet

Anwendungsbeschreibung

• Anwendungsbeschreibung: Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation.

Bilder

Human melanoma tumor cell pellets for assessment of proteins and their phosphorylation status