MRT67307, CAS [[1190378-57-4]]

Produktübersicht

• Artikelname: MRT67307, CAS [[1190378-57-4]]
• Artikelnummer: TGM-T0097
• Hersteller Artikelnummer: T0097
• Alternativnummer: TGM-T0097-1MLX10MM(INDMSO),TGM-T0097-1MG,TGM-T0097-5MG,TGM-T0097-10MG,TGM-T0097-25MG,TGM-T0097-50MG,TGM-T0097-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: MRT67307

Produktbeschreibung

Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy. MRT67307 prevents the phosphorylation of IRF3 and the production of IFN-beta and increases toll-like receptor-induced IL-10 and IL-1ra secretion in macrophages. MRT67307 is a kinase inhibitor that has been shown to inhibit TBK1, MARK1-4, IKKepsilon, and NUAK1 (IC50 values are 19, 27-52, 160, and 230 nM, respectively), the salt-inducible kinases (SIKs, IC50s =250, 67, and 430 nM for SIK1, SIK2, and SIK3, respectively) and ULK1 and ULK2 (IC50s = 45 and 38 nM, respectively).

Produkteigenschaften

• Molekulargewicht: 464.6
• Reinheit: 0.9984
• CAS Nummer: [1190378-57-4]
• Formel: C26H36N6O2
• Target-Kategorie: IkappaB/IKK|||Autophagy