Cytochalasin A, a cell-permeable fungal toxin and oxidized derivative of cytochalasin B, is an inhibitor of HIV-1 protease (IC50 = 3 µM). It inhibits actin polymerization, interferes with microtubule assembly by reacting with sulfhydryl groups, and serves as an antibiotic and bactericidal active agent.
Molekulargewicht:
477.59
CAS Nummer:
[14110-64-6]
Formel:
C29H35NO5
Target-Kategorie:
Antifungal|||HIV Protease
T10928
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