Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 µM) and p300/CPB-associated factor (PCAF, IC50 = 5 µM). Garcinol has anti-inflammatory and anti-cancer activity. Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 µM and 7.39 µM, respectively.
