Desonide, CAS [[638-94-8]]

Artikelnummer: TGM-T1168
Artikelname: Desonide, CAS [[638-94-8]]
Artikelnummer: TGM-T1168
Hersteller Artikelnummer: T1168
Alternativnummer: TGM-T1168-1MLX10MM(INDMSO),TGM-T1168-1G,TGM-T1168-5G,TGM-T1168-200MG,TGM-T1168-500MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Alternative Synonym: Tridesilon , Locapred , Prednacinolone
Desonide (Prednacinolone) is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated as a homodimer into the nucleus, where transcription activation via glucocorticoid response elements within glucocorticoid-responsive genes occur. This agent induces transcription of genes coding for anti-inflammatory proteins, including lipocortin-1, interleukin-10, interleukin-1 receptor antagonist and neutral endopeptidase. Increased synthesis of lipocortin-1 has an inhibitory effect on phospholipase A2, which in turn inhibits the release of arachidonic acid, thereby controlling the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.
Molekulargewicht: 416.51
Reinheit: 99.29%
CAS Nummer: [638-94-8]
Formel: C24H32O6
Target-Kategorie: Glucocorticoid Receptor|||Apoptosis|||Huntingtin
T1168