NF-56-EJ40 hydrochloride is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 hydrochloride has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM.
Molekulargewicht:
516.46
Reinheit:
0.9933
CAS Nummer:
[2728500-80-7]
Formel:
C27H31Cl2N3O3
Target-Kategorie:
Succinate Receptor 1 (SUCNR1)
T12216L
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