PQCA is a muscarinic M1 receptor-positive allosteric regulator, which is highly selective and effective. PQCA exhibited EC50 values of 49 nM in rhesus monkey and 135 nM in human M1 receptors, but showed no activity against other muscarinic receptors. PQCA is a potential compound for reducing cognitive deficits associated with Alzheimers disease.
Molekulargewicht:
388.42
Reinheit:
98.95%
CAS Nummer:
[1144504-35-7]
Formel:
C22H20N4O3
Target-Kategorie:
AChR
T12531
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